if you are flashing a v25 or v28 i would get a sata pci card
http://tekgems.com/Products/la-pci22-vt6421l.htm
if you are doing one of the hit drives.i would say try and see.
on the hit drives i yse a usb kit
http://www.divineo.com/cgi-bin/div-us/dd-360-xusb
this guild will help a lot.
http://www.360mods.net/Downloads/details/id=61.html